THERAPEUTIC TARGET DATABASE

The picture on the left exhibit a database which provides useful information about the known and explored therapuetic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. This database also includes other relevent features such as the 3D structure of the drug. ligand binding properties and many more information which can be extracted by a single click of the mouse. I have chosen a particular disease to show how this database works. For example, Myocardial Infarction.

This is how it looks when i enter myocardial infarction into the search engine. This page shows its specific therapeutic target of drug of myocardial infarction disease.In order to know more about the drug which serves the the target and action site. you should click on the linked code of the drug " Tenecteplase " .                   

                                              

once you have clicked the link just now, you will come to this page which shows sufficient information of this particular drug. looking at the target bar, the target site for myocardial infarction is known as "Fibrin-specific tissue plasminogen" in order to gain the information on its mechanism and how the drug works on the target site, you would be able to see the reference link.



This is where it goes. the website of US National Library of Medicine National Institute of Health. This website provides a brief information on the interaction of the drug and target site of myocardial infection disease. You can repeat this process for any kind of disease or target site.